Pub. Date : 2016 May
PMID : 26490035
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Inhibition of monoacylglycerol lipase (MAGL) enhances cue-induced reinstatement of nicotine-seeking behavior in mice. | Nicotine | monoglyceride lipase | Mus musculus |
| 2 | Inhibition of monoacylglycerol lipase (MAGL) enhances cue-induced reinstatement of nicotine-seeking behavior in mice. | Nicotine | monoglyceride lipase | Mus musculus |
| 3 | METHODS: Here, we investigated the effects of the MAGL inhibitor JZL184 on nicotine self-administration under fixed and progressive-ratio schedules of reinforcement and on cue-induced reinstatement of nicotine seeking in mice. | Nicotine | monoglyceride lipase | Mus musculus |
| 4 | MAGL inhibition by JZL184 (16 mg/kg) increased reinstatement of previously extinguished nicotine seeking induced by presentation of nicotine-associated cues, but did not produce reinstatement on its own. | Nicotine | monoglyceride lipase | Mus musculus |
| 5 | MAGL inhibition by JZL184 (16 mg/kg) increased reinstatement of previously extinguished nicotine seeking induced by presentation of nicotine-associated cues, but did not produce reinstatement on its own. | Nicotine | monoglyceride lipase | Mus musculus |