Pub. Date : 2015 Dec 11
PMID : 26487720
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Surprisingly, two-dimensional solid state NMR shows that the contact between Phe(19) and Leu(34) residues, observed in full-length Abeta and Abeta18-35, is still intact in these fibrils. | Leucine | amyloid beta precursor protein | Homo sapiens |
| 2 | We conclude that the self-assembly of Abeta is critically dependent on the hairpin turn and on the contact between the Phe(19) and Leu(34) regions, making them potentially sensitive targets for Alzheimer"s therapeutics. | Leucine | amyloid beta precursor protein | Homo sapiens |