Title : Structure-Activity Relationship of PEGylated Polylysine Peptides as Scavenger Receptor Inhibitors for Non-Viral Gene Delivery.

Pub. Date : 2015 Dec 7

PMID : 26485572






2 Functional Relationships(s)
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1 The scavenger receptor inhibition potency of PEG-peptides was dependent on the length of the Lys repeat, which increased 10-fold when comparing PEG30 kDa-Cys-Trp-Lys10 (IC50 of 20.2 muM) with PEG30 kDa-Cys-Trp-Lys25 (IC50 of 2.1 muM). Tryptophan latexin Homo sapiens
2 The scavenger receptor inhibition potency of PEG-peptides was dependent on the length of the Lys repeat, which increased 10-fold when comparing PEG30 kDa-Cys-Trp-Lys10 (IC50 of 20.2 muM) with PEG30 kDa-Cys-Trp-Lys25 (IC50 of 2.1 muM). Tryptophan latexin Homo sapiens