Title : Activity of Isavuconazole and Other Azoles against Candida Clinical Isolates and Yeast Model Systems with Known Azole Resistance Mechanisms.

Pub. Date : 2016 Jan

PMID : 26482310






1 Functional Relationships(s)
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1 Relative increases of azole MICs (from 4- to 32-fold) were observed for fluconazole, voriconazole, and isavuconazole when at least two mutations were present in the same ERG11 allele. Azoles sterol 14-demethylase Saccharomyces cerevisiae S288C