Title : Inhibition of human cytochrome P450 isoenzymes by a phenothiazine neuroleptic levomepromazine: An in vitro study.

Pub. Date : 2015 Dec

PMID : 26481538






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 CYP isoenzyme activities were determined using the CYP-specific reactions: caffeine 3-N-demethylation (CYP1A2), diclofenac 4"-hydroxylation (CYP2C9), perazine N-demethylation (CYP2C19), bufuralol 1"-hydroxylation (CYP2D6) and testosterone 6beta-hydroxylation (CYP3A4). Diclofenac cytochrome P450 family 4 subfamily F member 3 Homo sapiens
2 CYP isoenzyme activities were determined using the CYP-specific reactions: caffeine 3-N-demethylation (CYP1A2), diclofenac 4"-hydroxylation (CYP2C9), perazine N-demethylation (CYP2C19), bufuralol 1"-hydroxylation (CYP2D6) and testosterone 6beta-hydroxylation (CYP3A4). Diclofenac cytochrome P450 family 4 subfamily F member 3 Homo sapiens