Title : Pharmacological Targeting SHP-1-STAT3 Signaling Is a Promising Therapeutic Approach for the Treatment of Colorectal Cancer.

Pub. Date : 2015 Sep

PMID : 26476076






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Our previous data demonstrated that regorafenib (Stivarga) is a pharmacological agonist of SH2 domain-containing phosphatase 1 (SHP-1) that enhances SHP-1 activity and induces apoptosis by targeting STAT3 signals in CRC. regorafenib signal transducer and activator of transcription 3 Homo sapiens