Title : JNJ-26481585 primes rhabdomyosarcoma cells for chemotherapeutics by engaging the mitochondrial pathway of apoptosis.

Pub. Date : 2015 Nov 10

PMID : 26473375






1 Functional Relationships(s)
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1 Mechanistically, JNJ-26481585/Doxorubicin cotreatment causes upregulation of the BH3-only proteins Bim and Noxa as well as downregulation of the antiapoptotic proteins Mcl-1 and Bcl-xL. Doxorubicin BCL2 like 1 Homo sapiens