Title : Metformin affects the features of a human hepatocellular cell line (HepG2) by regulating macrophage polarization in a co-culture microenviroment.

Pub. Date : 2015 Nov

PMID : 26467463






2 Functional Relationships(s)
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1 RESULTS: Metformin induced single-cultured RAW264.7 macrophages with an M2 phenotype but attenuated the M2 macrophage differentiation and inhibited monocyte chemoattractant protein-1 (MCP-1) secretion in a co-culture system. Metformin C-C motif chemokine ligand 2 Homo sapiens
2 RESULTS: Metformin induced single-cultured RAW264.7 macrophages with an M2 phenotype but attenuated the M2 macrophage differentiation and inhibited monocyte chemoattractant protein-1 (MCP-1) secretion in a co-culture system. Metformin C-C motif chemokine ligand 2 Homo sapiens