Title : Downregulation of P-gp, Ras and p-ERK1/2 contributes to the arsenic trioxide-induced reduction in drug resistance towards doxorubicin in gastric cancer cell lines.

Pub. Date : 2015 Nov

PMID : 26459009






2 Functional Relationships(s)
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1 Downregulation of P-gp, Ras and p-ERK1/2 contributes to the arsenic trioxide-induced reduction in drug resistance towards doxorubicin in gastric cancer cell lines. Doxorubicin mitogen-activated protein kinase 3 Homo sapiens
2 Non- and mildly-toxic doses of As2O3 reduced MDR to DOX through Ras/p-ERK1/2 signaling. Doxorubicin mitogen-activated protein kinase 3 Homo sapiens