Title : Macrophage migration inhibitory factor (MIF) is rendered enzymatically inactive by myeloperoxidase-derived oxidants but retains its immunomodulatory function.

Pub. Date : 2015 Dec

PMID : 26453918






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 MIF has an unusual nucleophilic N-terminal proline with catalytic tautomerase activity. Proline macrophage migration inhibitory factor Homo sapiens
2 We hypothesized that MPO-derived oxidants would oxidize the N-terminal proline of MIF and alter its biological activity. Proline macrophage migration inhibitory factor Homo sapiens