Title : PARK7/DJ-1 dysregulation by oxidative stress leads to magnesium deficiency: implications in degenerative and chronic diseases.

Pub. Date : 2015 Dec

PMID : 26453619






6 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 SLC41A1 (solute carrier family 41 member 1), the gene encoding a ubiquitous cellular Mg(2+)E (Mg(2+)efflux) system, has been shown to be regulated by activated AR. Magnesium solute carrier family 41 member 1 Homo sapiens
2 SLC41A1 (solute carrier family 41 member 1), the gene encoding a ubiquitous cellular Mg(2+)E (Mg(2+)efflux) system, has been shown to be regulated by activated AR. Magnesium solute carrier family 41 member 1 Homo sapiens
3 SLC41A1 (solute carrier family 41 member 1), the gene encoding a ubiquitous cellular Mg(2+)E (Mg(2+)efflux) system, has been shown to be regulated by activated AR. Magnesium solute carrier family 41 member 1 Homo sapiens
4 SLC41A1 (solute carrier family 41 member 1), the gene encoding a ubiquitous cellular Mg(2+)E (Mg(2+)efflux) system, has been shown to be regulated by activated AR. Magnesium solute carrier family 41 member 1 Homo sapiens
5 We hypothesize that overexpression/up-regulation of PARK7/DJ-1, attributable to OS and related activation of AR, is an important event regulating the expression of SLC41A1 and consequently, modulating the Mg(2+)E capacity. Magnesium solute carrier family 41 member 1 Homo sapiens
6 Imipramine, in use as an antidepressant, has been shown to reduce the Mg(2+)E activity of SLC41A1 and OS. Magnesium solute carrier family 41 member 1 Homo sapiens