Title : APP overexpression in the absence of NPC1 exacerbates metabolism of amyloidogenic proteins of Alzheimer's disease.

Pub. Date : 2015 Dec 15

PMID : 26433932






1 Functional Relationships(s)
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1 Moreover, markers of oxidative stress were increased in vulnerable brain regions of ANPC mice and enhanced beta-CTF/Abeta levels increased susceptibility of N2a-ANPC cells to H2O2-induced toxicity. Hydrogen Peroxide amyloid beta (A4) precursor protein Mus musculus