Title : Osthol attenuates neutrophilic oxidative stress and hemorrhagic shock-induced lung injury via inhibition of phosphodiesterase 4.

Pub. Date : 2015 Dec

PMID : 26432981






1 Functional Relationships(s)
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1 In this study, our data showed that osthol potently inhibited the production of superoxide anion (O2( -)) and reactive oxidants derived therefrom as well as expression of CD11b in N-formylmethionylleucylphenylalanine (FMLP)-activated human neutrophils. N-Formylmethionine Leucyl-Phenylalanine formyl peptide receptor 1 Homo sapiens