Title : Induction of proinflammatory cytokine production in intervertebral disc cells by macrophage-like THP-1 cells requires mitogen-activated protein kinase activity.

Pub. Date : 2016 Jan

PMID : 26431069






1 Functional Relationships(s)
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1 Administration of 10 muM PD98059 significantly decreased IL-6 levels in the AF-MPhi coculture, and decreased the levels of TNF alpha and IL-8 in both the AF-MPhi and NP-MPhi cocultures. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one C-X-C motif chemokine ligand 8 Homo sapiens