Pub. Date : 2015 Oct 13
PMID : 26429859
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Here, we show that a novel pan-HDACi AR-42 downregulates CD44, a glycoprotein that has been associated with lenalidomide and dexamethasone resistance in myeloma both in vitro and in vivo. | Lenalidomide | CD44 molecule (Indian blood group) | Homo sapiens |
| 2 | Thus, our findings shed light on potential novel combinatorial therapeutic approaches modulating CD44 expression, which may help overcome lenalidomide resistance in myeloma patients. | Lenalidomide | CD44 molecule (Indian blood group) | Homo sapiens |