Title : Stimulation of a calcium-dependent actin nucleation activity by phorbol 12-myristate 13-acetate in rabbit macrophage cytoskeletons.

Pub. Date : 1989 Jan 17

PMID : 2642389






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Cytoskeletons of detergent-extracted quiescent macrophages have nucleation sites that increase the rate of pyrene-labeled actin assembly in vitro. pyrene actin Oryctolagus cuniculus
2 Cytochalasin D, which inhibits actin assembly at the fast-exchanging ends of filaments (barbed with respect to heavy meromyosin decorated filaments), only partially inhibits the increased assembly rate, demonstrating that pyrene-actin monomers add to both ends of filaments present in the cytoskeletons. pyrene actin Oryctolagus cuniculus