Pub. Date : 2015
PMID : 26412948
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Our results demonstrated that PGE2 promoted zymosan-induced IL-23 production in a concentration dependent manner. | Zymosan | interleukin 23 subunit alpha | Homo sapiens |
| 2 | More importantly, ELISA data demonstrated that db-cAMP, a cAMP analog, and forskolin, an adenylate cyclase activator, can mimic the effect of PGE2 on zymosan-induced IL-23 production, and rp-cAMP, a protein kinase A (PKA) inhibitor, can block the effect of PGE2. | Zymosan | interleukin 23 subunit alpha | Homo sapiens |
| 3 | Moreover, PGE2 can increase zymosan-induced expression of the mRNA levels of both p19 and p40 subunits, which was mimicked by db-cAMP and forskolin. | Zymosan | interleukin 23 subunit alpha | Homo sapiens |