Title : Evaluation of In Vitro Activity of the Class I PI3K Inhibitor Buparlisib (BKM120) in Pediatric Bone and Soft Tissue Sarcomas.

Pub. Date : 2015

PMID : 26402468






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Buparlisib inhibited activation of Akt and signaling molecules downstream of mTORC1 (mTOR complex 1) in Ewing sarcoma, osteosarcoma, and rhabdomyosarcoma cell lines. NVP-BKM120 AKT serine/threonine kinase 1 Homo sapiens