Title : A Critical Proton MR Spectroscopy Marker of Alzheimer's Disease Early Neurodegenerative Change: Low Hippocampal NAA/Cr Ratio Impacts APOE ɛ4 Mexico City Children and Their Parents.

Pub. Date : 2015

PMID : 26402110






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Decreases in NAA/Cr correlate well with cognitive function, behavioral symptoms, and dementia severity; thus, since the progression of AD starts decades before clinical diagnosis, our findings support the hypothesis that under chronic exposures to fine particulate matter and ozone above the standards, neurodegenerative processes start in childhood and APOE e4 carriers are at higher risk. Ozone apolipoprotein E Homo sapiens