Title : Synthesis of Biotinylated Inositol Hexakisphosphate To Study DNA Double-Strand Break Repair and Affinity Capture of IP6-Binding Proteins.

Pub. Date : 2015 Oct 20

PMID : 26397942






2 Functional Relationships(s)
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Protein Name
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1 We found that IP6-biotin could affinity capture Ku and other required NHEJ factors from human cell extracts, including the DNA-dependent protein kinase catalytic subunit (DNA-PKcs), XRCC4, and XLF. ip6-biotin X-ray repair cross complementing 4 Homo sapiens
2 DNA-PKcs, XLF, and the XRCC4:ligase IV complex interact with Ku in cell extracts and likely interact indirectly with IP6-biotin. ip6-biotin X-ray repair cross complementing 4 Homo sapiens