Pub. Date : 2015 Oct
PMID : 26377631
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | MUTYH is a base excision repair (BER) enzyme that prevents mutations in DNA associated with 8-oxoguanine (OG) by catalyzing the removal of adenine from inappropriately formed OG:A base-pairs. | Adenine | mutY DNA glycosylase | Homo sapiens |
2 | Both R295C and R520Q MUTYH were found to have low fractions of active enzyme, compromised affinity for damaged DNA, and reduced rates for adenine excision. | Adenine | mutY DNA glycosylase | Homo sapiens |