Title : Phosphorylation of TRPV1 by cyclin-dependent kinase 5 promotes TRPV1 surface localization, leading to inflammatory thermal hyperalgesia.

Pub. Date : 2015 Nov

PMID : 26376215






3 Functional Relationships(s)
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1 Recently, Cdk5 has been reported to phosphorylate TRPV1 at threonine 407 (Thr-407) in humans (Thr-406 in rats), which enhances the function of TRPV1 channel and promotes thermal hyperalgesia in the complete Freund"s adjuvant (CFA)-induced inflammatory pain rats. Threonine cyclin dependent kinase 5 Homo sapiens
2 Recently, Cdk5 has been reported to phosphorylate TRPV1 at threonine 407 (Thr-407) in humans (Thr-406 in rats), which enhances the function of TRPV1 channel and promotes thermal hyperalgesia in the complete Freund"s adjuvant (CFA)-induced inflammatory pain rats. Threonine cyclin dependent kinase 5 Homo sapiens
3 Recently, Cdk5 has been reported to phosphorylate TRPV1 at threonine 407 (Thr-407) in humans (Thr-406 in rats), which enhances the function of TRPV1 channel and promotes thermal hyperalgesia in the complete Freund"s adjuvant (CFA)-induced inflammatory pain rats. Threonine cyclin dependent kinase 5 Homo sapiens