Title : Inhibition of AMPK through Lyn-Syk-Akt enhances FcεRI signal pathways for allergic response.

Pub. Date : 2016 Feb

PMID : 26373430






1 Functional Relationships(s)
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1 When AMPK was activated by AICAR, A769662 and metformin, FcepsilonRI-mediated Syk, ERK, JNK and p38 activation, and TNFalpha release were all inhibited. 4-hydroxy-3-(4-(2-hydroxyphenyl)phenyl)-6-oxo-7H-thieno(2,3-b)pyridine-5-carbonitrile mitogen activated protein kinase 14 Rattus norvegicus