Title : Thymine DNA glycosylase exhibits negligible affinity for nucleobases that it removes from DNA.

Pub. Date : 2015 Oct 30

PMID : 26358812






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Initiating base excision repair, TDG removes thymine from mutagenic G : T mispairs caused by 5-methylcytosine (mC) deamination and other lesions including uracil (U) and 5-hydroxymethyluracil (hmU). 5-Methylcytosine thymine DNA glycosylase Homo sapiens
2 Initiating base excision repair, TDG removes thymine from mutagenic G : T mispairs caused by 5-methylcytosine (mC) deamination and other lesions including uracil (U) and 5-hydroxymethyluracil (hmU). 5-Methylcytosine thymine DNA glycosylase Homo sapiens
3 In DNA demethylation, TDG excises 5-formylcytosine (fC) and 5-carboxylcytosine (caC), which are generated from mC by Tet (ten-eleven translocation) enzymes. 5-Methylcytosine thymine DNA glycosylase Homo sapiens