Pub. Date : 2016 Jan
PMID : 26355761
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Homoplantaginin Inhibits Palmitic Acid-induced Endothelial Cells Inflammation by Suppressing TLR4 and NLRP3 Inflammasome. | Palmitic Acid | toll like receptor 4 | Homo sapiens |
2 | Firstly, we found that homoplantaginin (0.1, 1, 10 muM) dose-dependently reduced expression of toll-like receptor-4 evoked by PA (100 muM). | Palmitic Acid | toll like receptor 4 | Homo sapiens |
3 | In addition, downstream adapted proteins including myeloid differentiation primary response gene 88, toll/interleukin-1 receptor-domain containing adaptor-inducing interferon-beta and tumor necrosis factors receptor associated factor-6 were successfully inhibited by homoplantaginin under PA treatment. | Palmitic Acid | toll like receptor 4 | Homo sapiens |