Title : Homoplantaginin Inhibits Palmitic Acid-induced Endothelial Cells Inflammation by Suppressing TLR4 and NLRP3 Inflammasome.

Pub. Date : 2016 Jan

PMID : 26355761






3 Functional Relationships(s)
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1 Homoplantaginin Inhibits Palmitic Acid-induced Endothelial Cells Inflammation by Suppressing TLR4 and NLRP3 Inflammasome. Palmitic Acid toll like receptor 4 Homo sapiens
2 Firstly, we found that homoplantaginin (0.1, 1, 10 muM) dose-dependently reduced expression of toll-like receptor-4 evoked by PA (100 muM). Palmitic Acid toll like receptor 4 Homo sapiens
3 In addition, downstream adapted proteins including myeloid differentiation primary response gene 88, toll/interleukin-1 receptor-domain containing adaptor-inducing interferon-beta and tumor necrosis factors receptor associated factor-6 were successfully inhibited by homoplantaginin under PA treatment. Palmitic Acid toll like receptor 4 Homo sapiens