Title : Association of ABCB1, ABCC5 and xanthine oxidase genetic polymorphisms with methotrexate adverse reactions in Mexican pediatric patients with ALL.

Pub. Date : 2015 Sep

PMID : 26353179






2 Functional Relationships(s)
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Protein Name
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1 Association of ABCB1, ABCC5 and xanthine oxidase genetic polymorphisms with methotrexate adverse reactions in Mexican pediatric patients with ALL. Methotrexate ATP binding cassette subfamily B member 1 Homo sapiens
2 Single nucleotide polymorphisms (SNPs) of ABCB1 1236C>T (OR 0.19, 95% CI: 0.03-0.9, p<0.05) and ABCC5 3933+313T>C (OR 0.12, 95% CI: 0.027-0.58, p<0.05) were associated with methotrexate ADRs. Methotrexate ATP binding cassette subfamily B member 1 Homo sapiens