Title : Tristetraprolin mediates anti-inflammatory effects of carbon monoxide on lipopolysaccharide-induced acute lung injury.

Pub. Date : 2015 Nov

PMID : 26348577






7 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Tristetraprolin mediates anti-inflammatory effects of carbon monoxide on lipopolysaccharide-induced acute lung injury. Carbon Monoxide zinc finger protein 36 Mus musculus
2 With the use of TTP knockout mice, we demonstrate here that the protection by carbon monoxide against LPS-induced ALI is mediated by TTP. Carbon Monoxide zinc finger protein 36 Mus musculus
3 With the use of TTP knockout mice, we demonstrate here that the protection by carbon monoxide against LPS-induced ALI is mediated by TTP. Carbon Monoxide zinc finger protein 36 Mus musculus
4 Inhalation of carbon monoxide substantially increased the pulmonary expression of TTP. Carbon Monoxide zinc finger protein 36 Mus musculus
5 Moreover, knockout of TTP abrogated the anti-inflammatory and tissue-protective effects of carbon monoxide in LPS-induced ALI. Carbon Monoxide zinc finger protein 36 Mus musculus
6 These results suggest that carbon monoxide-induced TTP mediates the protective effect of carbon monoxide against LPS-induced ALI by enhancing the decay of mRNA encoding proinflammatory cytokines. Carbon Monoxide zinc finger protein 36 Mus musculus
7 These results suggest that carbon monoxide-induced TTP mediates the protective effect of carbon monoxide against LPS-induced ALI by enhancing the decay of mRNA encoding proinflammatory cytokines. Carbon Monoxide zinc finger protein 36 Mus musculus