Pub. Date : 2015 Dec
PMID : 26343345
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Atorvastatin and sildenafil decrease vascular TGF-beta levels and MMP-2 activity and ameliorate arterial remodeling in a model of renovascular hypertension. | Sildenafil Citrate | transforming growth factor, beta 1 | Rattus norvegicus |
2 | We hypothesized that atorvastatin and sildenafil alone or in association exert antiproliferative effects by down-regulating MMP-2 and TGF-beta, thus reducing the vascular hypertrophy induced by two kidney, one clip (2K1C) hypertension. | Sildenafil Citrate | transforming growth factor, beta 1 | Rattus norvegicus |
3 | Atorvastatin and sildenafil was associated with decreased vascular TGF-beta levels and MMP-2 activity in renovascular hypertensive rats, thus ameliorating the vascular remodeling. | Sildenafil Citrate | transforming growth factor, beta 1 | Rattus norvegicus |