Title : Interaction of Yna1 and Yna2 Is Required for Nuclear Accumulation and Transcriptional Activation of the Nitrate Assimilation Pathway in the Yeast Hansenula polymorpha.

Pub. Date : 2015

PMID : 26335797






3 Functional Relationships(s)
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1 Interaction of Yna1 and Yna2 Is Required for Nuclear Accumulation and Transcriptional Activation of the Nitrate Assimilation Pathway in the Yeast Hansenula polymorpha. Nitrates rRNA (cytosine-C5-)-methyltransferase NOP2 Saccharomyces cerevisiae S288C
2 The genes necessary for nitrate assimilation are organised in this organism as a cluster comprising those encoding nitrate reductase (YNR1), nitrite reductase (YNI1), a high affinity transporter (YNT1), as well as the two pathway specific Zn(II)2Cys2 transcriptional activators (YNA1, YNA2). Nitrates rRNA (cytosine-C5-)-methyltransferase NOP2 Saccharomyces cerevisiae S288C
3 Yna1p activates YNA2 as well as its own (YNA1) transcription thus forming a nitrate-dependent autoactivation loop. Nitrates rRNA (cytosine-C5-)-methyltransferase NOP2 Saccharomyces cerevisiae S288C