Pub. Date : 2015
PMID : 26329549
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The first finding is that the oral bioavailability of cyclosporine A (CsA), which is an immunosuppressant, was decreased by increased first-pass metabolism due to elevated CYP3A and P-glycoprotein (P-gp) specifically in the upper small intestine after liver I/R. | Cyclosporine | ATP-binding cassette, subfamily B (MDR/TAP), member 1B | Rattus norvegicus |
2 | The first finding is that the oral bioavailability of cyclosporine A (CsA), which is an immunosuppressant, was decreased by increased first-pass metabolism due to elevated CYP3A and P-glycoprotein (P-gp) specifically in the upper small intestine after liver I/R. | Cyclosporine | ATP-binding cassette, subfamily B (MDR/TAP), member 1B | Rattus norvegicus |
3 | The first finding is that the oral bioavailability of cyclosporine A (CsA), which is an immunosuppressant, was decreased by increased first-pass metabolism due to elevated CYP3A and P-glycoprotein (P-gp) specifically in the upper small intestine after liver I/R. | Cyclosporine | ATP-binding cassette, subfamily B (MDR/TAP), member 1B | Rattus norvegicus |
4 | The first finding is that the oral bioavailability of cyclosporine A (CsA), which is an immunosuppressant, was decreased by increased first-pass metabolism due to elevated CYP3A and P-glycoprotein (P-gp) specifically in the upper small intestine after liver I/R. | Cyclosporine | ATP-binding cassette, subfamily B (MDR/TAP), member 1B | Rattus norvegicus |