Pub. Date : 2016 Nov
PMID : 26320741
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The IRAK-ERK-p67phox-Nox-2 axis mediates TLR4, 2-induced ROS production for IL-1beta transcription and processing in monocytes. | Reactive Oxygen Species | mitogen-activated protein kinase 1 | Homo sapiens |
| 2 | In the present study, we demonstrate that the TLR4- and TLR2-induced IRAK-ERK pathway cross-talks with p67phox-Nox-2 for ROS generation, thus regulating IL-1beta transcription and processing in monocytic cells. | Reactive Oxygen Species | mitogen-activated protein kinase 1 | Homo sapiens |