Title : Impairment of neutrophil oxidative burst in children with sickle cell disease is associated with heme oxygenase-1.

Pub. Date : 2015 Dec

PMID : 26315932






1 Functional Relationships(s)
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1 We have previously shown that the liberation of heme in acute hemolysis can induce heme oxygenase-1 during granulopoiesis, impairing the ability of developing neutrophils to mount a bactericidal oxidative burst, and increasing susceptibility to bacterial infection. Heme heme oxygenase 1 Homo sapiens