Title : MicroRNA-143 Activation Regulates Smooth Muscle and Endothelial Cell Crosstalk in Pulmonary Arterial Hypertension.

Pub. Date : 2015 Oct 23

PMID : 26311719






3 Functional Relationships(s)
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1 We observed that miR-143-3p is selectively upregulated compared with miR-143-5p during PASMC migration. pasmc microRNA 143 Homo sapiens
2 In addition, we found high abundance of miR-143-3p in PASMC-derived exosomes. pasmc microRNA 143 Homo sapiens
3 Using assays with pulmonary arterial endothelial cells, we demonstrated a paracrine promigratory and proangiogenic effect of miR-143-3p-enriched exosomes from PASMC. pasmc microRNA 143 Homo sapiens