Title : Sulforaphane inhibits damage-induced poly (ADP-ribosyl)ation via direct interaction of its cellular metabolites with PARP-1.

Pub. Date : 2015 Nov

PMID : 26310710






1 Functional Relationships(s)
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1 PARP-1 is a stimulating factor for DNA SSBR-rate and we further demonstrated that 25 muM sulforaphane also delayed the rejoining of H2 O2 -induced DNA strand breaks, although this might be partly due to increased lesion frequencies. Hydrogen Peroxide poly(ADP-ribose) polymerase 1 Homo sapiens