Pub. Date : 2015 Nov
PMID : 26303110
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | CDRLTG values of the patients carrying the UGT1A4*3 genotype were higher compared to UGT1A4*1*1 (2.86 +- 1.03 vs 2.22 +- 0.94 mug/mL per mg/kg, p = 0.001) only when the VPA concentration was higher. | Valproic Acid | UDP glucuronosyltransferase family 1 member A4 | Homo sapiens |
2 | CONCLUSIONS: UGT1A4*3 polymorphism had an effect on LTG concentration only with VPA co-administration, and the effect was remarkable when VPA concentration was higher. | Valproic Acid | UDP glucuronosyltransferase family 1 member A4 | Homo sapiens |