Pub. Date : 2015 Sep 30
PMID : 26302161
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Inhibition of p53 activity using either pifithrin-alpha or small interference RNA interference reduced OGD-induced cell death and pifithrin-alpha reversed OGD-induced impairment of glutamate uptake in astrocytes, suggesting that p53 might play a key role in mediating neurotoxicity and gliotoxicity in ischemic brain injury. | pifithrin | tumor protein p53 | Homo sapiens |
| 2 | Inhibition of p53 activity using either pifithrin-alpha or small interference RNA interference reduced OGD-induced cell death and pifithrin-alpha reversed OGD-induced impairment of glutamate uptake in astrocytes, suggesting that p53 might play a key role in mediating neurotoxicity and gliotoxicity in ischemic brain injury. | pifithrin | tumor protein p53 | Homo sapiens |