Title : Acute reactive oxygen species (ROS)-dependent effects of IL-1β, TNF-α, and IL-6 on the glomerular filtration barrier (GFB) in vivo.

Pub. Date : 2015 Nov 1

PMID : 26290366






1 Functional Relationships(s)
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1 In conclusion IL-1beta, TNF-alpha, and IL-6, when infused systemically, caused immediate and partly reversible increases in glomerular permeability, which could be inhibited by the superoxide scavenger tempol, suggesting an important role of ROS in acute cytokine-induced permeability changes in the GFB. tempol tumor necrosis factor Rattus norvegicus