Title : Tandem Benzophenone Amino Pyridines, Potent and Selective Inhibitors of Human Leukotriene C4 Synthase.

Pub. Date : 2015 Oct

PMID : 26283693






1 Functional Relationships(s)
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1 In coincubations of platelets and polymorphonuclear leukocytes, inhibition of LTC4S led to shunting of LTA4 toward anti-inflammatory lipoxin A4, which was significantly enhanced by simultaneous inhibition of LTA4H. lipoxin A4 leukotriene C4 synthase Homo sapiens