Title : DNA binding fluorescent proteins for the direct visualization of large DNA molecules.

Pub. Date : 2016 Jan 8

PMID : 26264666






1 Functional Relationships(s)
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1 We report a novel design for a fluorescent, DNA-binding protein (FP-DBP) that completely "paints" entire DNA molecules, whereby sequence-independent DNA binding is accomplished by linking a fluorescent protein to two small peptides (KWKWKKA) using lysine for binding to the DNA phosphates, and tryptophan for intercalating between DNA bases. Phosphates zinc finger protein 763 Homo sapiens