Title : Nordihydroguaiaretic acid ameliorates cisplatin induced nephrotoxicity and potentiates its anti-tumor activity in DMBA induced breast cancer in female Sprague-Dawley rats.

Pub. Date : 2015 Sep

PMID : 26247680






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1 The protective effect of NDGA against cisplatin induced nephrotoxicity in the rats was further confirmed by significant restoration of antioxidant enzymes like SOD (86.28% inhibition), inflammatory markers like TNF-alpha (34.6 pg/ml) and histopathological examination. Masoprocol tumor necrosis factor Rattus norvegicus