Title : DNA repair by MGMT, but not AAG, causes a threshold in alkylation-induced colorectal carcinogenesis.

Pub. Date : 2015 Oct

PMID : 26243310






1 Functional Relationships(s)
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Protein Name
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1 NOC induce DNA alkylations, including O (6)-methylguanine (O (6)-MeG) and N-methylated purines, which are repaired by O (6)-MeG-DNA methyltransferase (MGMT) and N-alkyladenine-DNA glycosylase (AAG)-initiated base excision repair, respectively. o (6)-meg O-6-methylguanine-DNA methyltransferase Mus musculus