Title : Preclinical Efficacy and Safety Assessment of an Antibody-Drug Conjugate Targeting the c-RET Proto-Oncogene for Breast Carcinoma.

Pub. Date : 2015 Dec 15

PMID : 26240273






1 Functional Relationships(s)
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1 The fully human anti-RET antibody (Y078) was conjugated to the DM1 and DM4 derivatives of the potent cytotoxic agent maytansine using thioether and disulfide linkers, respectively. Sulfides ret proto-oncogene Homo sapiens