Pub. Date : 2015 Oct 15
PMID : 26220977
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Of the eight cis-meQTL SNPs, only the intronic CHRNB4 SNP rs11636753 was associated with CHRNA5 methylation independently of the known SNP effects in prefrontal cortex, and it was the most significantly associated SNP with nicotine dependence across five independent cohorts (total N = 7858 European ancestry and 3238 AA participants): P = 6.7 x 10(-4), odds ratio (OR) [95% confidence interval (CI)] = 1.11 (1.05-1.18). | Nicotine | cholinergic receptor nicotinic beta 4 subunit | Homo sapiens |