Title : Investigation of the reactivation kinetics of a large series of bispyridinium oximes with organophosphate-inhibited human acetylcholinesterase.

Pub. Date : 2016 Feb 26

PMID : 26210933






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1 In order to get more insight into the ability of bispyridinium oximes to reactivate human AChE inhibited by structurally different OP the reactivation kinetics of 31 compounds was determined with tabun-, cyclosarin- and paraoxon-inhibited AChE under identical experimental conditions. cyclohexyl methylphosphonofluoridate acetylcholinesterase (Cartwright blood group) Homo sapiens