Title : Factors Governing P-Glycoprotein-Mediated Drug-Drug Interactions at the Blood-Brain Barrier Measured with Positron Emission Tomography.

Pub. Date : 2015 Sep 8

PMID : 26202880






1 Functional Relationships(s)
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1 In this work we evaluated different factors which could influence the magnitude of the interaction between tariquidar and (R)-[(11)C]verapamil or [(11)C]-N-desmethyl-loperamide at the BBB and thereby contribute to previously observed species differences between rodents and humans. tariquidar ALMS1, centrosome and basal body associated Mus musculus