Title : Characterization of the metabolism of benzaldehyde dimethane sulfonate (NSC 281612, DMS612).

Pub. Date : 2015 Sep

PMID : 26193988






3 Functional Relationships(s)
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Protein Name
Organism
1 Of available ALDH isoforms ALDH1A1, ALDH3A1, ALDH2, and ALDH5A1, only ALDH1A1 converted BEN to BA. Barium aldehyde dehydrogenase 1 family member A1 Homo sapiens
2 Of available ALDH isoforms ALDH1A1, ALDH3A1, ALDH2, and ALDH5A1, only ALDH1A1 converted BEN to BA. Barium aldehyde dehydrogenase 1 family member A1 Homo sapiens
3 CONCLUSION: The activating conversion of BEN to BA is mediated not by CYP450 enzymes or aldehyde oxidase, but by ALDH1A1. Barium aldehyde dehydrogenase 1 family member A1 Homo sapiens