Title : Thrombin generation, ProC(®)Global, prothrombin time and activated partial thromboplastin time in thawed plasma stored for seven days and after methylene blue/light pathogen inactivation.

Pub. Date : 2016 Jan

PMID : 26192785






7 Functional Relationships(s)
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1 RESULTS: The velocity of thrombin generation increased significantly after methylene blue treatment (increased thrombin generation rate; time to peak decreased) and decreased after storage (decreased thrombin generation rate and peak thrombin; increased lag time and time to peak). Methylene Blue coagulation factor II, thrombin Homo sapiens
2 RESULTS: The velocity of thrombin generation increased significantly after methylene blue treatment (increased thrombin generation rate; time to peak decreased) and decreased after storage (decreased thrombin generation rate and peak thrombin; increased lag time and time to peak). Methylene Blue coagulation factor II, thrombin Homo sapiens
3 RESULTS: The velocity of thrombin generation increased significantly after methylene blue treatment (increased thrombin generation rate; time to peak decreased) and decreased after storage (decreased thrombin generation rate and peak thrombin; increased lag time and time to peak). Methylene Blue coagulation factor II, thrombin Homo sapiens
4 RESULTS: The velocity of thrombin generation increased significantly after methylene blue treatment (increased thrombin generation rate; time to peak decreased) and decreased after storage (decreased thrombin generation rate and peak thrombin; increased lag time and time to peak). Methylene Blue coagulation factor II, thrombin Homo sapiens
5 The endogenous thrombin generation potential remained stable after methylene blue treatment and storage at 4 C. Methylene blue treatment and 7 days of storage at 4 C activated the protein C pathway, whereas storage at room temperature and storage after methylene blue treatment decreased the functional capacity of the protein C pathway. Methylene Blue coagulation factor II, thrombin Homo sapiens
6 The endogenous thrombin generation potential remained stable after methylene blue treatment and storage at 4 C. Methylene blue treatment and 7 days of storage at 4 C activated the protein C pathway, whereas storage at room temperature and storage after methylene blue treatment decreased the functional capacity of the protein C pathway. Methylene Blue coagulation factor II, thrombin Homo sapiens
7 The endogenous thrombin generation potential remained stable after methylene blue treatment and storage at 4 C. Methylene blue treatment and 7 days of storage at 4 C activated the protein C pathway, whereas storage at room temperature and storage after methylene blue treatment decreased the functional capacity of the protein C pathway. Methylene Blue coagulation factor II, thrombin Homo sapiens