Pub. Date : 2015 Sep
PMID : 26184482
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Nicotine Induces Tumor Growth and Chemoresistance through Activation of the PI3K/Akt/mTOR Pathway in Bladder Cancer. | Nicotine | AKT serine/threonine kinase 1 | Homo sapiens |
| 2 | Phospho-specific Akt (pAkt) and phospho-specific p70 S6 kinase (pS6) were significantly upregulated by nicotine exposure. | Nicotine | AKT serine/threonine kinase 1 | Homo sapiens |
| 3 | In conclusion, nicotine increases tumor growth and induces acquired chemoresistance through activation of the PI3K/Akt/mTOR pathway in bladder cancer. | Nicotine | AKT serine/threonine kinase 1 | Homo sapiens |