Title : Activating mitochondrial function and haemoglobin expression with EH-201, an inducer of erythropoietin in neuronal cells, reverses memory impairment.

Pub. Date : 2015 Oct

PMID : 26177968






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1 In the hippocampus of mice given EH-201 in their diet, levels of erythropoietin, PGC-1alpha and haemoglobin were increased CONCLUSIONS AND IMPLICATIONS: The induction of endogenous erythropoietin in neuronal cells by inducers such as EH-201 might be a therapeutic strategy for memory impairment in neurodegenerative disease, physiological ageing or traumatic brain injury. 2,3,5,4'-tetrahydroxystilbene 2-O-glucopyranoside peroxisome proliferative activated receptor, gamma, coactivator 1 alpha Mus musculus