Title : Impacts of the Glucuronidase Genotypes UGT1A4, UGT2B7, UGT2B15 and UGT2B17 on Tamoxifen Metabolism in Breast Cancer Patients.

Pub. Date : 2015

PMID : 26176234






3 Functional Relationships(s)
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1 Impacts of the Glucuronidase Genotypes UGT1A4, UGT2B7, UGT2B15 and UGT2B17 on Tamoxifen Metabolism in Breast Cancer Patients. Tamoxifen UDP glucuronosyltransferase family 2 member B15 Homo sapiens
2 This descriptive study examines correlations between concentrations of tamoxifen"s glucuronide metabolites and genotypes UGT1A4 Pro24Thr, UGT1A4 Leu48Val, UGT2B7 His268Tyr, UGT2B15 Asp85YTyr UGT2B15 Lys523Thr and UGT2B17del in 132 patients with estrogen receptor-positive breast cancer under treatment with tamoxifen. Tamoxifen UDP glucuronosyltransferase family 2 member B15 Homo sapiens
3 This descriptive study examines correlations between concentrations of tamoxifen"s glucuronide metabolites and genotypes UGT1A4 Pro24Thr, UGT1A4 Leu48Val, UGT2B7 His268Tyr, UGT2B15 Asp85YTyr UGT2B15 Lys523Thr and UGT2B17del in 132 patients with estrogen receptor-positive breast cancer under treatment with tamoxifen. Tamoxifen UDP glucuronosyltransferase family 2 member B15 Homo sapiens